Beta-carotene is a secondary plant compound from the carotenoid family, which occur as natural pigments in fruits and vegetables. The bright yellow, orange and red shades of these foods are due to carotenoids.
There are about 700 different carotenes, of which the body can convert roughly 50 into vitamin A. The best-known and most important of these is beta-carotene, which has the highest vitamin A activity. Because beta-carotene is an important precursor of vitamin A, it is also called provitamin A.
As beta-carotene is converted into vitamin A in the body, it indirectly affects a wide range of bodily functions. Vitamin A has a cell-protective effect and is important for cell growth. It particularly supports the regeneration of the skin and mucous membranes, making it more difficult for pathogens to penetrate the skin barrier. Strengthening the body’s natural defences with beta-carotene may also help prevent degenerative diseases such as Alzheimer’s. A vitamin A deficiency can show up as irritated, sensitive or very dry skin, since this vitamin plays a key role in skin formation.
Vitamin A also plays an important role in bone stability and mucous membrane function. For example, vitamin A is important for the gastric mucosa, stomach walls and gastric juices. A healthy mucous membrane helps protect the stomach walls from acidic gastric juice. It is therefore no coincidence that regular consumption of foods rich in vitamin A, alpha- and beta-carotene can halve the risk of stomach cancer.
Due to its antioxidant action, beta-carotene is also thought to have a protective effect against other cancers, including cancers of the oesophagus, liver, pancreas, rectum, prostate, ovaries and cervix.
Numerous studies have confirmed that foods high in carotenoids can significantly reduce the risk of heart attack. Other studies indicate that two carotenoids in particular, beta-carotene and lycopene (found in tomatoes), can effectively reduce the risk of stroke. By lowering the risk of cardiovascular disease, they also help reduce peripheral arterial disease (PAD). Beta-carotene reduces the oxidation of LDL cholesterol in the body and thus protects against elevated cholesterol levels. This inhibits the formation of arterial calcification and narrowing.
As an antioxidant, beta-carotene positively affects brain function by improving communication between brain cells. It can also prolong the life of brain cells through its antioxidant action. In the form of vitamin A, beta-carotene also influences the processing of the protein beta-amyloid. This is particularly significant because faulty processing of this protein is associated with increased susceptibility to Alzheimer’s disease.
Oxidative damage from excessive free radicals in the body often leads to inflammatory processes. During inflammation, interleukin-6, an inflammatory marker, is released by white blood cells. The more interleukin-6 measured in the blood, the stronger the inflammation in the body. Scientific studies have shown that a high level of interleukin-6 is often associated with a low level of carotenoids. An increase in carotenoid levels can lead to a decrease in interleukin-6 levels.
Beta-carotene thus acts as an anti-inflammatory antioxidant and helps reduce cellular damage caused by so-called free radicals. When free radicals are neutralised by antioxidants such as beta-carotene, they are no longer able to alter or destroy genetic material. They can no longer negatively affect the body’s structures.
Vitamin A is also known as the eye vitamin — and for good reason. The retina is home to millions of cells responsible for perceiving light, colours and other visual stimuli. In a highly complex chain reaction triggered by specialised molecules, these stimuli are transmitted to the brain as visual images for processing. Vitamin A plays a major role in this process: without it, vision would not be possible. Vitamin A deficiency can lead to visual disturbances, including drying of corneal cells, burning eyes and conjunctival inflammation. In severe cases, macular degeneration can even develop.
Certain diseases, particularly of the liver, gallbladder or pancreas, impair the absorption of fat-soluble vitamins such as vitamin A. How much beta-carotene is absorbed also depends on the fat content of the diet. Poor diet or malnutrition can lead to an insufficient intake of carotenoids.
The need for vitamin A is further increased by cigarette smoking or inhaling polluted air. Environmental toxins such as cadmium accelerate the breakdown of vitamin A. In addition, there is a risk of vitamin A deficiency with high stress, inflammation or after surgery. Regular, moderate or excessive alcohol consumption also interferes with the absorption, storage and mobilisation of vitamin A.
A beta-carotene deficiency occurs when the body is unable, for health reasons, to absorb or properly utilise beta-carotene. This can lead to a vitamin A deficiency with adverse health consequences. Deficiency symptoms may include night blindness, fatigue, skin problems and a weakened immune system. A carotenoid deficiency can thus increase susceptibility to infections and the risk of atherosclerotic heart disease.
The risk of various cancers, such as laryngeal, lung or prostate cancer, is increased with a beta-carotene deficiency. Hair, nails, bones and nerves can also be affected by a carotenoid deficiency. In children, growth disorders can occur, and women may experience fertility problems.
There are no specific reference values for beta-carotene, but there are recommendations for daily vitamin A intake. To compare values, specialised units such as “retinol equivalents” (RE) and “retinol activity equivalents” (RAE) are used. Retinol activity equivalents take into account, in addition to vitamin A concentration, how efficiently the vitamin can be absorbed from food and how it behaves in combination with other nutrients. One microgram of retinol is considered equivalent to about 12 micrograms of beta-carotene.
Consuming beta-carotene does not lead to excessive vitamin A intake, because the body only converts what it needs. Excess beta-carotene not converted into vitamin A is stored in the fat cells under the skin and can discolour the skin orange-brown. Therefore, drinking one to two glasses of carrot juice a day and consuming about 15–30 mg of beta-carotene can result in a slight orange tint to the skin after about four to six weeks.
The many health benefits of beta-carotene — from cancer prevention to supporting heart health — make it a valuable nutrient that can be optimally utilised through a balanced diet rich in colourful fruit and vegetables.


