The well-known component of coffee is, of course, caffeine. “Coffee is often equated with caffeine, but coffee beans actually contain over 100 biologically active compounds. These substances can help reduce oxidative stress and inflammation, improve insulin sensitivity, boost metabolism, inhibit fat absorption in the gut, and block receptors known to be involved in abnormal heart rhythms,” says Dr Peter M. Kistler, professor and head of arrhythmia research at the Alfred Hospital and Baker Heart Institute in Melbourne, Australia.
In fact, scientific studies using decaffeinated coffee often show the same effects as caffeinated coffee. So it is not only about caffeine. In addition to hundreds of other substances, coffee provides us with potassium, magnesium, calcium, antioxidant chlorogenic acid, carbohydrates, proteins, oils and 100 aroma compounds that create coffee's distinctive bitterness – including, naturally, caffeine.
The health effects of coffee also depend on how it is prepared. Espresso and filter coffee are regarded as healthier than some other brewing methods.
When preparing espresso, high pressure is used to force hot water through the finely ground coffee. As a result, espresso contains less acidity and is better tolerated by people with a sensitive stomach.
When preparing filter coffee, the substances cafestol and kahweol are retained in the filter; in high amounts these can raise the cholesterol level.
After drinking a cup of coffee, the body's hormone gastrin is released in increased amounts. This leads to a higher production of hydrochloric acid, which sensitive people may not tolerate well.
The food bolus is broken down faster and passed into the intestine. There, coffee stimulates the muscle contractions in the colon wall and thus activates peristalsis.
Chlorogenic acid, which is abundant in coffee, also has a digestion-promoting effect: it stimulates bile flow and helps digest fats. In addition, coffee causes our bodies to produce more the digestive hormone cholecystokinin. This hormone is responsible for releasing certain digestive enzymes and contributes to bile production by stimulating the contraction of the gallbladder.
Moreover, the bitter compound caffeine is absorbed through the stomach and small intestine within 30 minutes after drinking coffee and is distributed throughout the body. Essentially, caffeine behaves like an everyday drug, as its chemical structures resemble those of amphetamines such as cocaine or methamphetamine. People react very differently to this “drug”. Their reaction partly depends on whether the liver metabolises caffeine slowly or quickly.
Another factor is the sensitivity of the central nervous system to caffeine's stimulating properties. If someone has a slow liver metabolism and a strong binding in the central nervous system, even small amounts of caffeine will have a stimulating effect. People with a good balance between liver inactivation of caffeine and its binding in the central nervous system can drink up to five cups of coffee a day without suffering from sleep problems. With low sensitivity to caffeine, larger amounts can be consumed and one can even drink a cup of coffee before bedtime, as caffeine is then metabolised quickly by the body.
Studies suggest that regular coffee consumption can boost metabolism during exercise, reduce the risk of type 2 diabetes and colorectal cancer, and have a slight positive effect on life expectancy. Regular consumption of three to five cups of filter coffee a day can lower the risk of coronary heart disease and stroke – and this applies even to people with high blood pressure. In addition, unsweetened black coffee can protect against tooth decay: the chlorogenic acid, nicotinic acid and trigonelline it contains kill decay-causing bacteria. These positive health effects apply to coffee both with and without caffeine.
However, too much coffee is not healthy and can cause insomnia, increased blood pressure, malaise, stomach problems and nausea and reduce fertility. High amounts of caffeine increase the release of the stress hormone adrenaline, making it harder to relax.
Furthermore, caffeine is structurally similar to the neurotransmitter adenosine. Adenosine tells our body when we need rest and sleep. Caffeine blocks its receptors, so you may not feel sleepy but still feel constantly tired. The brain can also become accustomed to caffeine. Pregnant women should avoid coffee completely: caffeine crosses the placenta into the baby's blood and can harm it.
With these tips you can enjoy your coffee with a clear conscience, so that this beverage, rich in hundreds of plant compounds, becomes part of your healthy lifestyle!


