The nasal mucosa plays an important role as a barrier between the human body and the outside world. It warms, filters and humidifies thousands of litres of air every day without us noticing. A runny nose, also called rhinitis, occurs when the nasal mucosa is inflamed, either acutely or chronically.
The entire surface of the respiratory mucosa is covered with cells that have movable hair‑like structures on their surface. These cilia have the important task of transporting foreign particles such as dust and allergens away. This keeps our airways clean. The cilia move these particles in waves towards the throat, so they can be coughed up more easily. Often foreign particles do not even reach the throat because a sneeze expels them prematurely.
When the nasal mucosa dries out, for example from heated indoor air, the cilia stick together and the nose's cleansing function is impaired. Pathogens such as bacteria and viruses can then settle on the mucous membranes. An inflammatory reaction follows: the mucosa swells and mucus production increases. The nose runs or becomes blocked.
The common acute runny nose is often associated with respiratory infections caused by viral or bacterial infections. In dry, heated rooms and in cold outdoor temperatures our nasal mucosa tend to dry out, which favours the entry of pathogens and can trigger inflammation. This causes the familiar nasal discharge.
The secretions are usually clear, similar to allergic rhinitis. Affected people often feel tired and worn out, accompanied by headache and muscle aches.
Rhinoviruses and coronaviruses, but also other viruses such as myxo-, Coxsackie- or parainfluenza viruses are the most frequent agents of colds and rhinitis. They are mainly transmitted via droplet infection, for example when a person with a cold sneezes near another person.
Transmission can also occur by contact (contact transmission). For example, if a person with a cold blows their nose or sneezes into their hand and then touches a door handle or a rail on public transport, viruses are transferred to these surfaces. A healthy person can then become infected if they touch that spot and then put their hand to their mouth or nose.
In medicine, rhinitis is classified as acute or chronic depending on its duration. An acute rhinitis is often caused by cold viruses, especially when the immune system is weakened, e.g. by chilling, poor nutrition or psychological factors such as stress. A bacterial infection (secondary infection) often occurs in addition and may be noticeable by the production of yellowish‑green mucus when sneezing or coughing. Compared with acute rhinitis, chronic, persistent rhinitis is more difficult to treat.
Besides the common acute rhinitis, there are other forms. These include allergic rhinitis, such as hay fever, triggered by allergens. Drug‑induced rhinitis, also called rhinitis medicamentosa, occurs as a reaction to certain medications. Gustatory rhinitis appears after eating spicy foods, and vasomotor rhinitis is a form caused by disturbed regulation of the blood vessels in the nasal mucosa.
There are various triggers for vasomotor rhinitis, also referred to as idiopathic, non‑infectious or non‑allergic rhinitis. These include moving from a warm room to cold outdoor temperatures, drinking hot beverages or alcohol and stress. This form includes subgroups such as senile rhinitis, gravid rhinitis and rhinitis medicamentosa. Overreaction to certain triggers such as temperature changes, stress, certain foods (e.g. spicy seasonings) or environmental pollutants leads to temporary dilation of blood vessels in the chronically inflamed nasal mucosa, accompanied by sneezing and watery nasal discharge. The exact cause is often unknown and the precise mechanism has not yet been fully clarified.
Allergic rhinitis can occur seasonally, as in hay fever, or year‑round. Triggers include house dust mites (dust allergy), animal dander (e.g. cat allergy), mould spores (mould allergy) or certain foods (food allergy). Swelling of the nasal mucosa, watery‑clear nasal secretions and sneezing attacks with itching characterise allergic rhinitis. Over time the nasal mucosa often dries out. Allergic rhinitis frequently occurs together with conjunctivitis.
A number of toxic or irritating substances in the environment, including at the workplace, can cause rhinitis. In medical terminology this is called toxic‑irritative rhinitis. Potential triggers include sulphur dioxide, carbon dioxide, carbon monoxide, ozone, cigarette smoke, solvents, pesticides, metals, varnishes, paints, disinfectants and dusts.
Hormonal changes, for example during pregnancy, puberty, menopause, in acromegaly (excess production of growth hormone somatotropin) or in hypothyroidism, can also trigger susceptibility to respiratory infections. In medical terminology this condition is referred to as hormonal rhinitis.
Inflammation of the nasal mucosa in rhinitis can often extend to the mucosa of the paranasal sinuses. The increased accumulation of mucus during a cold provides an ideal breeding ground for germs. Inflammations can develop and spread easily to the sinuses. When rhinitis and sinusitis occur together, clinicians refer to this as rhinosinusitis.
From the tiny cilia in our airways to the many causes ranging from viruses to environmental pollutants: colds show how sensitive our bodies are to external influences. The right measures to relieve symptoms can not only improve individual well‑being but also help prevent serious complications.


